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| Thesis Name： |
Concise total synthesis of (+)-carpamic acid |
| Usage： |
Synthesis of (+)-carpamic acid |
| Keyword： |
Concise total synthesis of (+)-carpamic acid. |
| Remarks： |
An enantioselective total synthesis of (+)-carpamic acid is reported. This concise synthesis is based on a novel concept of a selective cross-metathesis reaction with a subsequent diastereoselective cyclizing reductive amination.
We report herein an efficient enantioselective synthesis of (+)-carpamic acid, with nine steps as the longest linear sequence, the key strategy being based on a novel sequence of a cross-metathesis (CM) reaction and a subsequent cyclizing reductive amination to form the piperidine ring.
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| Original file： |
No File
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Promulgator Detail |
| Full name: |
hichem |
| Country: |
CN |
| City: |
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| Company Name: |
hichem |
| Homepage: |
http://www.teloon.com |
| E-mail: |
reply |
| Phone: |
86-411-82819585 |
| Fax: |
86-411-82819612 |
| Company Address: |
Renming Road, Dalian city, Lianning pro,china |
| Zip/Postal Code: |
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| Introduction: |
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