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  Site: Index >> Technology >> Chemical Thesis >> Thesis Detail

Thesis Name: new oligosaccharide synthesis using special hydroxy protecting group.
Usage: Protecting groups
Keyword: special hydroxy protecting group
Remarks: A new hydroxy protecting group for the convenient preparation of oligosaccharides has been developed using the uni-chemo protection (UCP) concept.
The UCP group comprises polymerized amino acid derivatives that protect each hydroxyl group by an ester linkage. With different degrees of polymerization, the hydroxyl groups were characterized and controlled.

Using this protecting group, two kinds of sialyl-T analogues were successfully synthesized from the same sugar units merely by repeating Edman degradation and coupling.
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